Synthesis and 1H-NMR configurational study of Δ3-Thiazolines from 2-Aza-1,3-dienes

Article abstract of DOI:10.1016/S0040-4020(01)81191-1

A <4 + 1> heterocyclization process involving 2-aza-1,3-dienes and elemental sulphur leading to the synthesis of Δ³-thiazolines with excellent yields is described.A ID TOCSY and ID NOESY study of these systems was made in order to establish the configuration of the diastereoisomeric mixture. Key Words: Δ³-thiazolines; 2-aza-1,3-dienes; <4+1>heterocyclization; 1D NOESY