Tetrahedron Letters p. 6389 - 6392 (1992)
Update date:2022-08-04
Topics:
Moree, Wilna J.
Van Der Marel, Gijs A.
Liskamp Rob
α-amino acids can be converted to homochiral β-substituted aminoethane sulfinamide or sulfonamide transition-state isosteres, which can be incorporated into peptides. These transition-state analogues e.g. the sulfonamide isostere of Phe-Phe will be used for the generation of catalytic antibodies as well as for the development of protease inhibitors.
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Doi:10.1016/j.tet.2004.07.027
(2004)Doi:10.1039/DT9920002679
(1992)Doi:10.1007/s00044-013-0796-9
(2014)Doi:10.1007/BF00864345
(1992)Doi:10.1016/0040-4039(93)88009-8
(1992)Doi:10.1021/ja00075a030
(1993)