A novel regio- and stereo-specific hydroacetoxylation reaction of 2-alkynoic acid derivatives

Article abstract of DOI:10.1016/S0040-4039(00)60873-0

2-Alkynoic acid derivatives were hydroacetoxylated regio- and stereo-specifically by reaction with lithium acetate in HOAc at rt under the catalysis of palladium acetate to afford 3-acetoxy-2(Z)-alkenoic acid derivatives.