Remarkable dependency of the regioselectivity in the ring opening of α,β-epoxyketones upon tin halide-Lewis base complexes as catalysts

Article abstract of DOI:10.1016/S0040-4039(00)60859-6

Tin halide-base complexes are used as catalysts for controlling the regioselectivity in the reaction of α,β-epoxyketones with electrophiles. Bu₂SnX₂-Ph₃P complex caused the cleavage of the C-O bond adjacent to the carbonyl