NEOLIGNANS OF VIROLA CARINATA BARK

Article abstract of DOI:10.1016/0031-9422(82)83107-5

Four neolignans, dehydrodieugenol, its monomethylether, carinatone and carinatin have been isolated from the hexane fraction of the bark of Virola carinata.Three new neolignans were separated from the chloroform fraction and examined by spectroscopy and chemical reactions.Their structures were determined as (2S,3S)-5-allyl-7-methoxy-3-hydroxymethyl-2-(3',4'-dimethoxyphenyl)-2,3-dihydrobenzofuran, (2S)-1-(3',4'-dimethoxyphenyl)-2-(3''-allyl-5''-methoxy-6''-hydroxyphenyl)propanone(1)ol(3), (1S,2S)-1-3',4'-dimethoxyphenyl)-2-(3''-allyl-5''-methoxy-6''-hydroxyphenyl)propanol(1) and called dihydrocarinatinol, carinatonol and carinatol, respectively. - Key Word Index: Virola carinata; Myristicaceae; bark; neolignans; dihydrocarinatinol; carinatonol; carinatol; NMR.