Tetrahedron Letters p. 5937 - 5940 (1987)
Update date:2022-08-03
Topics:
Bathgate, Antoinette
Malpass, John R.
Intramolecular cyclisation of trans-1-(benzylamino)-4-chlorocycloheptane and hept-2-ene gives the corresponding 8-azabicyclo(3.2.1)octane (nortropane) and -oct-6-ene (nortrop-6-ene) derivatives respectively.Under appropriate conditions, cyclohept-1,3-diene is converted into nortropane in 75percent overall yield.
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Doi:10.1007/BF00765116
(1987)Doi:10.1016/j.tetlet.2013.08.121
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(2013)Doi:10.1016/j.ica.2013.07.039
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(2013)
