Stereoselective one-pot method for the introduction of an amino group to a cyclohexane ring. Preparation of the octahydroisobenzofuro[7a,1-d]oxazole ring system

DOI: 10.1055/s-1992-26353

Source and publish data:

Synthesis p. 1261 - 1264 (1992)

Update date:2022-08-05

Topics:

Authors:

Saito Saito

Takagi Takagi

Yamamoto

Yamada Yamada

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Article abstract of DOI:10.1055/s-1992-26353

Stereoselective one-pot synthesis of octahydroisobenzofuro[7a,1-d]oxazole-2,5-diones 7-14 via base-catalyzed addition-cyclization reaction of hydroxy lactones 4a-4d with various isocyanates 5a-5f is described. The ring system contains diastereoselectively

Full text of DOI:10.1055/s-1992-26353

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