Tetrahedron p. 929 - 938 (1993)
Update date:2022-08-05
Topics: Synthesis Conversion Reagents Concise Regiospecific Organolithium Aromatic metallation Benzoic acids 4-hydroxy-1-arylnaphthalenes
Epsztajn, Jan
Jozwiak, Andrzej
Szczesniak, Aleksandra K.
The synthesis of the 3-unsubstituted phthalides (5) and their conversion into 1-hydroxy-1-arylphthalans (8), very useful precursors of isobenzofurans (10) and subsequent cycloaddition of them to dimethyl acetylenedicarboxylate as a way of regiospecific transformation of benzoic acids into dimethyl 4-hydroxy-1-(2-methoxyphenyl)naphthalene-2,3-dicarboxylates (12) (biaryls highly substituted around the axis), is described.
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Doi:10.1021/ja00365a075
(1982)Doi:10.1021/ja039175+
(2004)Doi:10.1021/jm00059a001
(1993)Doi:10.1021/acs.orglett.7b02784
(2017)Doi:10.1016/0223-5234(92)90110-M
(1992)Doi:10.1016/S0277-5387(03)00408-X
(2003)