Dopamine receptor agonists. I. Synthesis and phamacological evaluation of 4-aryl-substituted analogues of 6,7-dihydroxy-2-amino tetralin (6,7-ADTN) and related indane compounds

Article abstract of DOI:10.1016/0223-5234(92)90086-G

Derivatives of cis- and trans-4-phenyl-6,7-dihydroxy-2-aminotetraline and trans-1-phenyl-5,6-dihydroxy-2-aminoindane were synthetized as fenoldopam analogues. They showed no affinity for D₁ and D₂ binding sites in rat striatal membra