Efficient synthesis of 2′-O-alkyl ribonucleosides using trichloroacetimidateDribofuranosides as ribosyl donors

Article abstract of DOI:10.1016/S0040-4039(00)75987-9

Trichloroacetimidate-2-O-alkyl-3,5-O-TIPS-β- _D-ribofuranoside glycosylates silylated nucleobases in a fast high-yielding and stereo selective reaction promoted by trimethylsilyl trifluoromethanesulfonate. This method has been applied to the syn