Facile and selective deprotection of PMB ethers and esters using oxalyl chloride

DOI: 10.1016/j.tetlet.2015.01.061

Source and publish data:

Tetrahedron Letters p. 1081 - 1084 (2015)

Update date:2022-07-29

Topics: Solvent Work-Up Product Isolation

Authors:

Ilangovan, Andivelu

Anandhan, Karnambaram

Kaushik, Mahabir Prasad

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Article abstract of DOI:10.1016/j.tetlet.2015.01.061

Oxalyl chloride, (0.5 equiv) was found to cleave the PMB group from alkyl, aryl PMB ethers, and esters to give corresponding alcohol and acid in good yields. This method offers simple and efficient protocol for the selective deprotection of PMB ether and ester in DCE at ambient temperature.

Full text of DOI:10.1016/j.tetlet.2015.01.061

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