Synthesis of some guanylhydrazones and imidazolinylhydrazones as thromboxane-synthase and platelet aggregation inhibitors

Article abstract of DOI:10.1002/ardp.19923251206

The imidazolinylhydrazones of (3-pyridinyloxy)-acetaldehyde and of 6-[3(2-formyl-pyridinyl)oxy]hexanoic acid were synthesized as cyclic analogues of the corresponding guanylhydrazones which were found to be selective inhibitors of human thromboxane-syntha