
Journal of Medicinal Chemistry p. 3090 - 3099 (1994)
Update date:2022-08-04
Topics:
Warner
Green
Gomes
Strimpler
Human leukocyte elastase (HLE) is a serine protease produced by neutrophils that has been implicated in diseases such as amphysema and cystic fibrosis. An HLE inhibitor may have therapeutic value in these diseases. An active site model of HLE bound to a t
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