
Journal of the American Chemical Society p. 3407 - 3415 (1993)
Update date:2022-07-29
Topics:
Woo, Jinsuk
Sigurdsson, Snorri Th.
Hopkins, Paul B.
The site of DNA interstrand cross-linking identified by a family of pyrrole-derived bifunctional electrophiles was studied in vitro in synthetic DNA duplexes. This family includes reductively activated mitomycin C (1), oxidatively activated pyrrolizidine
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