SYNTHESIS OF α-AMINO-β-HYDROXY ACIDS USING KETENE BIS(TRIMETHYLSILYL) ACETAL OR ITS N-METHYL-N-TRIMETHYLSILYL ANALOG

DOI: 10.1016/S0040-4039(00)83885-X

Source and publish data:

Tetrahedron Letters p. 3807 - 3810 (1986)

Update date:2022-08-04

Topics:

Authors:

Hvidt, Torsten

Martin, Oliver R.

Szarek, Walter A.

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Article abstract of DOI:10.1016/S0040-4039(00)83885-X

Condensation of the title compounds with aldehydes and ketones in the presence of trimethylsilyl triflate provided the correspondig α-amino-β-hydroxy acids in fair to good yields as a mixture of diastereomers.

Full text of DOI:10.1016/S0040-4039(00)83885-X

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