Preparation of macrodiolides via a common chiral building block. Total synthesis of (-)-pyrenophorin and (-)-pyrenophorol

Article abstract of DOI:10.1016/0040-4039(93)89027-N

Macrodiolides (-)-pyrenophorin and (-)-pyrenophorol have been synthesized utilizing a C₂ symmetric (R,R)-diepoxide as a common enantiopure chiral building block.