Synthesis and reactions of methyl (trimethylsilylmethyl)-acetylenecarboxylate. A general method for the generation of di-exo-methyleneisoxazolines and novel access to fused isoxazoles

DOI: 10.1016/0040-4039(93)85108-9

Source and publish data:

Tetrahedron Letters p. 485 - 488 (1993)

Update date:2022-08-04

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Authors:

Hojo, Makoto

Tomita, Kyoji

Hosomi, Akira

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Article abstract of DOI:10.1016/0040-4039(93)85108-9

Methyl (trimethylsilylmethyl)acetylenecarboxylate, which is a common key compound in preparation of precursors for di-exo-methylene derivatives of isoxazolines, reacts with nitrile oxides to yield cycloadducts, isoxazoles. Reduction and acetylation of cyc

Full text of DOI:10.1016/0040-4039(93)85108-9

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