Chemistry of Heterocyclic Compounds p. 53 - 57 (1992)
Update date:2022-07-31
Topics:
Stoyanov, V. M.
El'chaninov, M. M.
Pozharskii, A. F.
1-Methyl-2-phenylimidazole reacts with butyllithium to give 5-lithium substituted products.On the other hand, 1-methyl-2-(furyl-2)imidazole is metallated under the same conditions exclusively on the furan ring and primarily in the 3 position.The introduction of triethylamine into the reaction mixture, or replacement of butyllithium by lithium 2,2,6,6-tetramethylpiperidide leads to the formation of a lithium derivative substituted at the 5-position of the furan ring exclusively.
View MoreContact:886 2 2541 0022
Address:8 Fl., No. 11, Sec. 1, Chung Shan North Rd., Taipei, Taiwan R.O.C.
Wuhan Soleado Technology Co.,Ltd.
Contact:86-2783341481 18971291927
Address:RM2405 Unit 1 Builing 1, Taiyin Tower, Changqing Road,Wuhan China
SuZhou Hua-Emy Chemical Import and Export Co., LTD.
Contact:+86-512-88804994; +86-512-88804550;
Address:710, Building B, International Trade Center, 12 Huanghelu, Changshu, Jiangsu,China
FOSHAN NANHAI ZHONGNAN PHARMACEUTICAL FACTORY
Contact:0086-0757-85609331
Address:XIAHENGTIAN INDUSTRIAL ZONE,SHAYONG VILLAGE,LISHUI TOWN
Shandong Shouguang Songchuan Industrial Additives Co.,Ltd
Contact:+86-536-8566856
Address:Shouguang,Shandong,China
Doi:10.1021/jm00060a001
(1993)Doi:10.1248/cpb.39.2247
(1991)Doi:10.1016/j.chempr.2019.10.016
(2019)Doi:10.1016/S0040-4020(01)86334-1
(1993)Doi:10.1021/jo00063a019
(1993)Doi:10.1007/BF00531472
(1992)
