Chemistry of Heterocyclic Compounds p. 53 - 57 (1992)
Update date:2022-07-31
Topics:
Stoyanov, V. M.
El'chaninov, M. M.
Pozharskii, A. F.
1-Methyl-2-phenylimidazole reacts with butyllithium to give 5-lithium substituted products.On the other hand, 1-methyl-2-(furyl-2)imidazole is metallated under the same conditions exclusively on the furan ring and primarily in the 3 position.The introduction of triethylamine into the reaction mixture, or replacement of butyllithium by lithium 2,2,6,6-tetramethylpiperidide leads to the formation of a lithium derivative substituted at the 5-position of the furan ring exclusively.
View MoreZhejiang Linhai Xinhua Chemicals Factory
Contact:0086-13661858911
Address:Xunqiao Development Zone, Linhai, Zhejiang, China
Jiangsu Fengshan Group Co., Ltd.
Contact:86-25-86558671
Address:1903,Central International Mansion 105-6 North Zhongshan Road, Nanjing, China
Contact:021-36356756
Address:Room601,Building No.14,280 Yangcheng Road,Shanghai
Contact:(86) 731 88718666
Address:Room 1222, Unit 4, Building B, Shangcheng, No.47, Kaiyuan East Road.
Contact:+86-518-81061113
Address:No. 8 Lingzhou Road, Lianyungang, Jiangsu, China
Doi:10.1021/jm00060a001
(1993)Doi:10.1248/cpb.39.2247
(1991)Doi:10.1016/j.chempr.2019.10.016
(2019)Doi:10.1016/S0040-4020(01)86334-1
(1993)Doi:10.1021/jo00063a019
(1993)Doi:10.1007/BF00531472
(1992)
