Journal of the American Chemical Society p. 11916 - 11920 (2018)
Update date:2022-08-04
Topics: Synthesis Stereoselective Cyclohexanes
Akhtar, Wasim M.
Armstrong, Roly J.
Frost, James R.
Stevenson, Neil G.
Donohoe, Timothy J.
An iridium catalyzed method for the synthesis of functionalized cyclohexanes from methyl ketones and 1,5-diols is described. This process operates by two sequential hydrogen borrowing reactions, providing direct access to multisubstituted cyclic products with high levels of stereocontrol. This methodology represents a novel (5 + 1) strategy for the stereoselective construction of the cyclohexane core.
View MoreHebei DaPeng Pharm & Chem Co., Ltd.
Contact:86-317-7298678,0576-88861898 88861908
Address:West Songmen Village, East Songmen Town, Wuqiao, Cangzhou, Hebei ,China
YanCheng LongShen Chemical Co.,Ltd.
Contact:+86-515-86668866
Address:No.13,Weiyi Road,Funing Aoyang Industrial Park
Contact:86-25-58619180
Address:Nanjing High-Tech Zone 10 Xinghuo Road Pukou District Nanjing, Jiangsu 210061 The People's Republic of China
Contact:021-36356756
Address:Room601,Building No.14,280 Yangcheng Road,Shanghai
SuZhou Ascepion Pharmaceuticals, Inc.(expird)
Contact:0512-86881668
Address:Building C,68Xingqing Road,Suzhou,China.
Doi:10.1111/cbdd.12134
(2013)Doi:10.1021/jm00062a011
(1993)Doi:10.1021/jo00063a044
(1993)Doi:10.1016/S0008-6215(00)80750-8
(1981)Doi:10.1021/jo00100a045
(1994)Doi:10.1016/S0277-5387(03)00193-1
(2003)
