Novel Cyclization by Stannyl Anion Generated from Me3SiSnBu3 and F(1-). The Application to the Natural Product Synthesis

DOI: 10.1021/jo00063a012

Source and publish data:

Journal of Organic Chemistry p. 2972 - 2976 (1993)

Update date:2022-08-04

Topics:

Authors:

Mori, Miwako

Isono, Naohiro

Kaneta, Naotake

Shibasaki, Masakatsu

Read Full Text PDF DownLoad Join now for total 90,000,000 free articles

Article abstract of DOI:10.1021/jo00063a012

Stannyl anion, generated from Me3SiSnBu3 and (Et2N)3S(1+)*TMSF2(1-) (TASF) or CsF in DMF, was quite effective for generation of an aryl or vinyl anion, which reacted with a carbonyl group intramolecularly to provide the useful cyclized product in good yield.

Full text of DOI:10.1021/jo00063a012

Products guided by the article

Product name:2-Methyl-2-((E)-3-trimethylsilanyl-allyl)-cyclohexane-1,3-dione

Cas No:147974-04-7

R&D Labs maybe for 147974-04-7

Chengdu King-tiger Pharm-chem. Tech. Co., Ltd

Contact:028-85317716

Address:Tianfu Life Science Park, No. 88 South Keyuan Road, Gaoxin District, Chengdu City, Sichuan Province, PRC.
Arshine Pharmaceutical Co., Limited

website:http://www.cnarshine.com

Contact:0731-88503671

Address:Room 1109.Block C3, Lugu Enterprise Plaza,No.27 Wenxuan Road,Changsha National Hi-Tech Industrial Development Zone,Hunan ,P.R.China
Synchemie Co., Ltd.

website:http://www.synchemie.com/

Contact:+86-574-87642758

Address:Room 901, Yinyi Bund Building， 132 Renmin Road
Jiangsu Zhenfang Chemical CO.,LTD.(Suzhou Zhenfang Chemical Factory)

Contact:+86-512-69598882

Address:Room1201, Jiayuan Road No.1018, Xiangcheng District, Suzhou, China
Zhejiang Rongkai Chemical Technology Co.,Ltd.

Contact:+86-578-8185786

Address:Shangjiang Industrial Zone,Suichang

Relevant to this article

Practical enantioselective arylation and heteroarylation of aldehydes with in situ prepared organotitanium reagents catalyzed by 3-aryl-H ₈-BINOL-derived titanium complexes

Doi:10.1002/chem.201203946
(2013)
Reactivity of α-Nitro Ketones toward Organometallic Reagents: Straightforward Synthesis of Tertiary β-Nitroalkanols

Doi:10.1021/jo00064a025
(1993)
The Synthesis of Novel GABA Uptake Inhibitors. 1. Elucidation of the Structure-Activity Studies Leading to the Choice of (R)-1-<4,4-Bis(3-methyl-2-thienyl)-3-butenyl>-3-piperidinecarboxylic Acid (Tiagabine) as an Anticonvulsant Drug Candidate

Doi:10.1021/jm00064a005
(1993)
Chemoenzymatic carbon-carbon bond formation leading to non-carbohydrate derivative. Stereoselective synthesis of pentamycin C-11-C-16 fragment

Doi:10.1248/cpb.41.282
(1993)
Unique zeolite-catalyzed synthesis of nitroketene S,N-acetals

Doi:10.1016/S0040-4020(01)86309-2
(1993)
Iodonium ion-assisted synthesis of a haptenic tetrasaccharide fragment corresponding to the inner cell-wall glycopeptidolipid of Mycobacterium avium serotype 4

Doi:10.1016/0008-6215(93)80102-K
(1993)

Article Doi