Conjugate addition of organocuprates to methyl crotonate linked to chiral oxazolidones

Article abstract of DOI:10.1080/00397919308009764

Conjugate addition of various sp3 dialkylcuprates were performed on enoates 4a-b, γ-aminocrotonate equivalents embodied in chiral oxazolidones. The diastereoselectivity is good to moderate and allows the access to homochiral β-substituted GABA analogues.

Full text of DOI:10.1080/00397919308009764

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Synthetic Communications: An
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Conjugate Addition of
Organocuprates to Methyl
Crotonate Linked to Chiral
Oxazolidones
Sylvie Le Coz a & André Mann a
a Laboratoire de Pharmacochimie Moléculaire ,
Centre de Neurochimie , 5 rue Blaise Pascal, 67084,
Strasbourg Cedex, France
Published online: 23 Sep 2006.
To cite this article: Sylvie Le Coz & André Mann (1993) Conjugate Addition of
Organocuprates to Methyl Crotonate Linked to Chiral Oxazolidones, Synthetic
Communications: An International Journal for Rapid Communication of Synthetic
Organic Chemistry, 23:2, 165-171, DOI: 10.1080/00397919308009764
To link to this article: http://dx.doi.org/10.1080/00397919308009764
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