MICROBIOLOGICAL REDUCTION OF KETO-SULFONES. APPLICATION IN A THREE-STEP SYNTHESIS OF (S)-(+)-β-ANGELICA LACTONE

Article abstract of DOI:10.1016/S0957-4166(00)82344-7

Microbiological reductions of several keto-sulfones led to the corresponding hydroxy-sulfones in moderate to high enantiomeric excess.A three-step synthesis of (S)-(+)-β-angelica lactone from ethyl-4-oxo-3-(phenyl-sulfonyl)pentanoate via the intermediate