Biocatalytic preparation of (R)-(-)-4-(phenylthio)-2-butanol and (R)-(-)-4-(Phenylsulfonyl)-2-butanol by the sequential use of Pichia farinosa and Rhodococcus rhodochrous

Article abstract of DOI:10.1246/cl.1996.233

Preparation of (R)-4-(phenylthio)-2-butanol and (R)-4-(phenylsulfonyl)-2-butanol has been established based on the sequential use of two biocatalysts. A Pichia farinosa IAM 4682 mediated reduction of 4-(phenylthio)-2-butanone afforded (R)-4-(phenylthio)-2