Intramolecular Hetero-Diels-Alder Reaction of N-Arylimines. Applications to the Synthesis of Octahydroacridine Derivatives

Article abstract of DOI:10.1021/jo00062a033

A new intramolecular Lewis acid catalyzed hetero-Diels-Alder reaction of N-arylimines 5 with nonactivated olefins tethered to the 2-azadiene system was developed in order to prepare 1,2,3,4,4a,9,9a,10-octahydroacridine derivatives 6.Both reactivity and ci