A convenient synthesis of aminoacids by a ZnBr2 promoted reaction of ketene bis(trimethylsilyl) acetals with aldimines

Article abstract of DOI:10.1080/00397919308009832

The ZnBr₂ promoted addition of ketene bis(trimethylsilyl) acetals to aromatic aldimines affords β-arylaminoacids in good to excellent yields. Under the same reaction conditions vinylic ketene bis(trimethylsilyl) acetals give exclusively or mainly δ-phenylaminoacids.

Full text of DOI:10.1080/00397919308009832

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Synthetic Communications: An
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Organic Chemistry
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A Convenient Synthesis
of Aminoacids by ZnBr2
Promoted Reaction of Ketene
bis(Trimethylsilyl) Acetals with
Aldimines
M. Mladenova a & M. Bellassoued b
a Institute of Organic Chemistry, Bulgarian Academy
of Sciences , 1113, Sofia, Bulgaria
b Laboratoire de Synthèse Organomètallique (URA
408), Université P. et M. Curie , 4, Place Jussieu,
B[acaron]t, F, 75230, Paris Cedex, 05, France
Published online: 23 Sep 2006.
To cite this article: M. Mladenova & M. Bellassoued (1993) A Convenient Synthesis
of Aminoacids by ZnBr2 Promoted Reaction of Ketene bis(Trimethylsilyl) Acetals
with Aldimines, Synthetic Communications: An International Journal for Rapid
Communication of Synthetic Organic Chemistry, 23:6, 725-736
To link to this article: http://dx.doi.org/10.1080/00397919308009832
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