SYNTHESIS OF 1-SUBSTITUTED DIHYDROPYRIMIDINONE AND QUINAZOLINONE DERIVATIVES

Article abstract of DOI:10.1007/BF00529585

Condensation of N-substituted β-alanines (synthesized from anthranilic acid or its esters and acrylic acid) with urea afforded the corresponding 1-substituted dihydropyrimidinedione and quinazolinedione.When potassium thiocyanate was employed in the reaction instead of urea, decarboxylation and desulfuration occurred.