Synthesis p. 321 - 324 (1993)
Update date:2022-08-03
Topics:
Genet
Thorimbert
Mallart
Kardos
The title compounds were conveniently synthesized by efficient sequential one-pot amination-alkylation starting from (Z)-4-acetoxy-2-butenyl ethyl carbonate (3) with tert-butyl (tert-butoxycarbonyl-oxy)carbamate, dimethylamine and methyl (diphenylmethyleneamino) acetate. Hydrogenation and hydrolysis of the 1,4-adducts afforded N6-hydroxylysine [2-amino-6-(hydroxyamino)hexanoic acid 1) and laminine hydrochloride [2-amino-6-(trimethylammonio)hexanoic acid chloride, 2] in 65% and 39% yield, respectively.
View MoreNINGXIA DARONG CHEMICALS & METALLURGY CO.,LTD.
Contact:86-952-2179751
Address:Darong Road, Dawukou, Shizuishan, Ningxia 753001, China
Jinhua City Mingzhu Pharmaceutical Co.,Ltd.
Contact:15857995878 0579-82207761
Address:No.169 Shenze Road, New Area,Jinpan Development Zone, Jinhua
Contact:+91 - 22 - 26355700
Address:17, Lotus Business Park, Andheri West
Jinzhou Jiutai Pharmaceutical Co.,Ltd
Contact:+86-0416-5179890
Address:No.41, Taianli, Taihe District, Jinzhou, Liaoning
Zhejiang Newfine Industry Co.,Ltd.
Contact:+86-573-82262042
Address:No.225,Dongqing Road, garoms@163.com
Doi:10.1021/jm00069a007
(1993)Doi:10.1080/00397911.2013.813547
(2014)Doi:10.1139/v04-088
(2004)Doi:10.1002/chem.201503744
(2016)Doi:10.1021/ja01878a026
(1939)Doi:10.1002/hlca.19460290314
(1946)