Studies on aromatase inhibitors. I. Synthesis and biological evaluation of 4-amino-4H-1,2,4-triazole derivatives

DOI: 10.1248/cpb.44.1871

Source and publish data:

Chemical and Pharmaceutical Bulletin p. 1871 - 1879 (1996)

Update date:2022-08-04

Topics:

Authors:

Okada, Minoru

Yoden, Toru

Kawaminami, Eiji

Shimada, Yoshiaki

Kudoh, Masafumi

Isomura, Yasuo

Shikama, Hisataka

Fujikura, Takashi

Read Full Text PDF DownLoad Join now for total 90,000,000 free articles

Article abstract of DOI:10.1248/cpb.44.1871

Various 4-N-substituted amino-4H-1,2,4-triazole derivatives were synthesized and evaluated for aromatase-inhibitory activity (in vitro) and for pregnant mare serum gonadotropin (PMSG)-induced estrogen synthesis- inhibitory activity (in vivo). The 4-(4-cya

Full text of DOI:10.1248/cpb.44.1871

NII-Electronic Library Service

Products guided by the article

Product name:4-[N-acetyl-N-(4-nitrophenyl)amino]-4H-1,2,4-triazole

Cas No:148869-71-0

R&D Labs maybe for 148869-71-0

TIANJIN NORTH JINHENG CHEMICAL PLANT.

Contact:0086-22-59952083

Address:DongShigu Country In JiXian TianJin China
Changzhou Litong Chemical Co., Ltd.

website:http://www.litonchem.com/

Contact:+86-519-86301238

Address:Laoba Rd, Hutang town Changzhou Jiangsu
Chongqing maohuan Chemicals Co., Ltd

website:http://www.bschem.com

Contact:+86 13996103726

Address:Chongqing Nan'an District Tu Town
Kaiping Genuine Biochemical Pharmaceutical Co.,Ltd.

Contact:+86-750-2881198

Address:No.1, Xinke Road, Shatang Town, Kaiping, Guangdong Province, P.R.China
Shanghai Mokai Pharmaceutical Co.,Ltd

Contact:021-60257269

Address:Rm506,No.915,Zhenbei Road,Shanghai,200333,China

Relevant to this article

Kinetic studies of the epimerization of diastereomeric pyrylium salts

Doi:10.1021/jo401620w
(2013)
The development of N-aryl trifluoroacetimidate-based benzyl and allyl protecting group reagents

Doi:10.1016/j.tetlet.2013.09.014
(2013)
Chemical synthesis of a comb-shaped, branched stereoregular polysaccharide, 4-O-α-D-mannopyranosyl-(1->6)-α-D-mannopyranan

Doi:10.1016/0008-6215(93)80030-I
(1993)
Doi:10.1021/jo01149a024
(1950)
Synthesis of fatty acyl derivatives of 24-epibrassinolide

Doi:10.1016/j.jsbmb.2013.01.016
(2013)
Kinetic resolution in vanadium-catalyzed sulfur oxidation as an efficient route to enantiopure aryl benzyl sulfoxides

Doi:10.1055/s-2006-944187
(2006)

Article Doi