Studies on aromatase inhibitors. I. Synthesis and biological evaluation of 4-amino-4H-1,2,4-triazole derivatives

DOI: 10.1248/cpb.44.1871

Source and publish data:

Chemical and Pharmaceutical Bulletin p. 1871 - 1879 (1996)

Update date:2022-08-04

Topics:

Authors:

Okada, Minoru

Yoden, Toru

Kawaminami, Eiji

Shimada, Yoshiaki

Kudoh, Masafumi

Isomura, Yasuo

Shikama, Hisataka

Fujikura, Takashi

Read Full Text PDF DownLoad Join now for total 90,000,000 free articles

Article abstract of DOI:10.1248/cpb.44.1871

Various 4-N-substituted amino-4H-1,2,4-triazole derivatives were synthesized and evaluated for aromatase-inhibitory activity (in vitro) and for pregnant mare serum gonadotropin (PMSG)-induced estrogen synthesis- inhibitory activity (in vivo). The 4-(4-cya

Full text of DOI:10.1248/cpb.44.1871

NII-Electronic Library Service

Products guided by the article

Product name:4-[N-acetyl-N-(4-nitrophenyl)amino]-4H-1,2,4-triazole

Cas No:148869-71-0

R&D Labs maybe for 148869-71-0

Guangxi Bonger Pharmaceutical Co., Ltd

website:http://napo.lookchem.com/

Contact:+86-18817331185

Address:Donghai Industrial Zone, Tiandong Country,Guangxi,China
Taizhou Shengxing Chempharm Co.,Ltd

Contact:+86-576-88516600

Address:Yantou Chemical Zone Jiaojiang Taizhou Zhejiang China
Shijiazhuang Yunxuan Im&Export Co.,Ltd.

Contact:+86-311-83037514

Address:No.6 Hongbin Road
Puyang Huicheng Electronic Material Co., Ltd

website:http://huichengchem.weba.testwebsite.cn/index_en.html

Contact:+86-393-8910800

Address:West Section Shengli Road, Puyang457000, China
Melone Pharmaceutical Co., ltd

Contact:+86-411 82593920, 82593631

Address:No 232, JInma Roda, Development Zone, Dalian, China

Relevant to this article

Kinetic studies of the epimerization of diastereomeric pyrylium salts

Doi:10.1021/jo401620w
(2013)
The development of N-aryl trifluoroacetimidate-based benzyl and allyl protecting group reagents

Doi:10.1016/j.tetlet.2013.09.014
(2013)
Chemical synthesis of a comb-shaped, branched stereoregular polysaccharide, 4-O-α-D-mannopyranosyl-(1->6)-α-D-mannopyranan

Doi:10.1016/0008-6215(93)80030-I
(1993)
Doi:10.1021/jo01149a024
(1950)
Synthesis of fatty acyl derivatives of 24-epibrassinolide

Doi:10.1016/j.jsbmb.2013.01.016
(2013)
Kinetic resolution in vanadium-catalyzed sulfur oxidation as an efficient route to enantiopure aryl benzyl sulfoxides

Doi:10.1055/s-2006-944187
(2006)

Article Doi