Studies on aromatase inhibitors. I. Synthesis and biological evaluation of 4-amino-4H-1,2,4-triazole derivatives

DOI: 10.1248/cpb.44.1871

Source and publish data:

Chemical and Pharmaceutical Bulletin p. 1871 - 1879 (1996)

Update date:2022-08-04

Topics:

Authors:

Okada, Minoru

Yoden, Toru

Kawaminami, Eiji

Shimada, Yoshiaki

Kudoh, Masafumi

Isomura, Yasuo

Shikama, Hisataka

Fujikura, Takashi

Read Full Text PDF DownLoad Join now for total 90,000,000 free articles

Article abstract of DOI:10.1248/cpb.44.1871

Various 4-N-substituted amino-4H-1,2,4-triazole derivatives were synthesized and evaluated for aromatase-inhibitory activity (in vitro) and for pregnant mare serum gonadotropin (PMSG)-induced estrogen synthesis- inhibitory activity (in vivo). The 4-(4-cya

Full text of DOI:10.1248/cpb.44.1871

NII-Electronic Library Service

Products guided by the article

Product name:4-[N-acetyl-N-(4-nitrophenyl)amino]-4H-1,2,4-triazole

Cas No:148869-71-0

R&D Labs maybe for 148869-71-0

Hangzhou Gangjin Chemical Co.,Ltd.(expird)

Contact:+86-571-85109780

Address:707 Zhejiang Minhang Bldg., No.290 Zhongshan North Road, Hangzhou 310003, China
LIAOYANG WANRONG CHEMICALS COMPANY LIMITED

Contact:86-419-2390789

Address:XINLI VILLAGE , DONG NINGWEI COUNTY,TAIZIHE DISTRICT, LIAOYANG , LIAONING
Dalian Synco Chemical Co., Ltd.

Contact:+86-411-83635150

Address:Rm 1004, 24, Tangshan Street, Dalian
Yangzhou Siyu Chemical Co.,Ltd.

Contact:+86-514-87325867 13358126196

Address:Room 620 Exposition Pavilion，No. 98 Huaihai Road,Guangling District，Yangzhou City, Jiangsu Province
WEIFANG DERUN CHEMICAL CO.,LTD

Contact:86-536-8956886

Address:weifang

Relevant to this article

Kinetic studies of the epimerization of diastereomeric pyrylium salts

Doi:10.1021/jo401620w
(2013)
The development of N-aryl trifluoroacetimidate-based benzyl and allyl protecting group reagents

Doi:10.1016/j.tetlet.2013.09.014
(2013)
Chemical synthesis of a comb-shaped, branched stereoregular polysaccharide, 4-O-α-D-mannopyranosyl-(1->6)-α-D-mannopyranan

Doi:10.1016/0008-6215(93)80030-I
(1993)
Doi:10.1021/jo01149a024
(1950)
Synthesis of fatty acyl derivatives of 24-epibrassinolide

Doi:10.1016/j.jsbmb.2013.01.016
(2013)
Kinetic resolution in vanadium-catalyzed sulfur oxidation as an efficient route to enantiopure aryl benzyl sulfoxides

Doi:10.1055/s-2006-944187
(2006)

Article Doi