Synthesis from D-lyxonolactone of 1,4-dideoxy-1,4-imino-L-arabinitol, a glucosidase inhibitor with in vitro anti-viral activity

DOI: 10.1016/S0040-4020(01)90163-2

Source and publish data:

Tetrahedron p. 3359 - 3366 (1993)

Update date:2022-09-26

Topics:

Authors:

Behling, James R.

Campbell, Arthur L.

Babiak, Kevin A.

Ng, John S.

Medic, John

Farid, Payman

Fleet, George W. J.

Read Full Text PDF DownLoad Join now for total 90,000,000 free articles

Article abstract of DOI:10.1016/S0040-4020(01)90163-2

Benzylidenation is the only protection required in a 7 step synthesis of the hydrochloride of 1,4-dideoxy-1,4-imino-L-arabinitol from D-lxyonolactone in an overall yield of 21%.

Full text of DOI:10.1016/S0040-4020(01)90163-2

Products guided by the article

Product name:3,5(S)-O-benzylidene-2-O-methanesulphonyl-D-lyxono-1,4-lactone

Cas No:149466-59-1

R&D Labs maybe for 149466-59-1

Hangzhou Haiqiang Chemical Co.,Ltd.

Contact:+86-571-86960370

Address:Add: 5/F, Around Town North Road,No. 10, Hangzhou, Zhejiang,China
Shandong united-rising pharmaceutical cooperation.,ltd.

Contact:008653187965009

Address:171No., Jing5 Road, Shizhong District, Jinan, China
Lishui Nanming Chemical Co., Ltd(expird)

Contact:+86-0578-2134101，2697830

Address:No.19 Tongji Road Shuige Industrial zone
TIANJIN ZHONGXIN CHEMTECH CO.,LTD.

Contact:86-022-66880623

Address:FINANCIAL STREET WEST BLK 7, #308, NO.52 XINCHENG WEST ROAD, TEDA, TIANJIN, P.R.CHINA
Shanghai Dano Pharmaceutical Co.,Ld.(expird)

Contact:+86-592-6266840

Address:Building 1 Room 512, 720 Cailun Rd, Zhangjiang High-Tech Park, Shanghai 201203, China

Relevant to this article

Dipolar HCP materials as alternatives to DMF solvent for azide-based synthesis

Doi:10.1039/d1gc02002a
(2021)
Periodic change in absorption maxima due to different chain packing between the bilayers of amphiphiles possessing even and odd numbers of carbons in the hydrophobic chain

Doi:10.1039/p29960002707
(1996)
Synthesis of Heterocyclic β-Amino Acids. A Convenient Preparation of β-Amino-5-Pyrimidinepropanoic Acid and Derivatives.

Doi:10.1016/S0040-4039(00)61438-7
(1993)
Amination of Arenes with Electron-Deficient Azodicarboxylates

Doi:10.1021/jo00082a035
(1994)
Replicative durons: Stereoselective Synthesis of Oligo-Tetrahydrofuranic Lactones via C-Glyeosylation with [(Trimethylsilyl)oxy]furan

Doi:10.1021/jo970212n
(1997)
Electrolytic Reactions of Fluoroorganic Compounds. 14. Regioselective Anodic Methoxylation of N-(Fluoroethyl)amines. Preparation of Highly Useful Fluoroalkylated Building Blocks

Doi:10.1021/jo00082a018
(1994)

Article Doi