Nucleic-Acid Analogues with Constraint Conformational Flexibility in the Sugar-Phosphate Backbone ('Bicyclo-DNA'), Part 1. Preparation of (3'S,5'R)-2'-Deoxy-3',5'-ethano-αβ-D-ribonucleosides ('Bicyclonucleosides')

DOI: 10.1002/hlca.19930760132

Source and publish data:

Helvetica Chimica Acta p. 481 - 510 (1993)

Update date:2022-09-26

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Authors:

Tarkoey, Markus

Bolli, Martin

Schweizer, Bernd

Leumann, Christian

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Article abstract of DOI:10.1002/hlca.19930760132

We describe the synthesis of 2'-deoxy-3',5'-ethano-D-ribonucleosides 1-8 (=(5',8'-dihydroxy-2'-oxabicyclo<3.3.0>oct-3'-yl)purines or -pyrimidines) of the nucleobases adenine, thymine, cytosine, and guanine.They differ from natural 2'-deoxyribonucleosides

Full text of DOI:10.1002/hlca.19930760132

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