Application of the Evans aziridination procedure to 2-substituted acrylates and cinnamates: An expedient route to α-substituted α- and β- amino acids

Article abstract of DOI:10.1016/S0040-4039(98)01132-0

Reaction of the title compounds with PhI = NSO₂Ar (Ar = p-tolyl or p- nitrophenyl) in the presence of catalytic copper (II) triflate in acetonitrile gave the corresponding 2 and/or 3-substituted aziridine-2- carboxylates in generally good yield