Carbon based nucleophilic ring opening of activated monocyclic β-lactams; synthesis and stereochemical assignment of the ACE inhibitor WF-10129

DOI: 10.1016/0040-4020(95)00157-4

Source and publish data:

Tetrahedron p. 4733 - 4762 (1995)

Update date:2022-09-26

Topics:

Authors:

Baldwin, Jack E.

Adlington, Robert M.

Russell, Andrew T.

Smith, Marie L.

Read Full Text PDF DownLoad Join now for total 90,000,000 free articles

Article abstract of DOI:10.1016/0040-4020(95)00157-4

The preparation of γ-keto α-amino acids via carbon based nucleophilic ring opening of activated monocyclic β-lactams was examined and applied to the synthesis and stereochemical assignment of the dipeptide angiotensin convering enzyme (ACE) inhibitor, WF-

Full text of DOI:10.1016/0040-4020(95)00157-4

Products guided by the article

Product name:(3S)-1-phenylsulphonyl 3-^tbutyldimethylsilyloxybutane

Cas No:150176-19-5

R&D Labs maybe for 150176-19-5

Baoding City Light Industry And Textiles Imp.& Exp. Corp. Chemical Department.

Contact:86-312-3262436

Address:NO.658 CHAOYANG SOUTH STREET,BAODING CITY HEBEI CHINA
shijiazhuang baisheng chem co.; ltd

Contact:86-0311-80790826

Address:shijiazhuang hebei
Shanghai Balmxy Pharmaceutical Co., Ltd

Contact:0086-21-24206007

Address:Room 402, 15#, No. 909 wangyue Road, shanghai, P. R. China
zonk drug r&d limited

Contact:+86-20-32051076

Address:1105,Building A, International Business Incubator,Science City
BAODING SINO-CHEM INDUSTRY CO.,LTD

Contact:0312-5956088

Address:NO.8 FUXING ROAD,CHINA

Relevant to this article

A versatile synthesis of α-Keto (cyanomethylene)triphenylphosphorane ylides from Alkyl halides utilizing a noble Phenylsulfonyl reagent

Doi:10.5012/bkcs.2013.34.10.2953
(2013)
Synthesis of 2-Tert-butylimino-3-hepta-O-benzoyl-β-D-lactosylimino-4- S-benzyl-6-arylimino-2,3-dihydro-1,3,5-thiadiazines

Doi:10.1080/00397911.2013.815214
(2014)
Acyloin Condensation of 1,2-Diacyloxyethanes; Directed Synthesis of Unsymmetrically Substituted 1,2-Bis-(trimethylsiloxy)ethenes

Doi:10.1002/prac.19953370114
(1995)
Synthesis and biological evaluation of novel 2-amino-3-aroyl-4-neopentyl-5- substituted thiophene derivatives as allosteric enhancers of the A₁ adenosine receptor

Doi:10.1016/j.bmc.2013.11.043
(2014)
3-Hydroxypyrroles and 1H-Pyrrol-3(2H)-ones. Part 13. Reactions of Methoxymethylene Meldrum's Acids with 3-Hydroxypyrroles, with 3-Methoxypyrroles and with other Active Substrates, and Pyrolytic Heterocyclizations of the Products

Doi:10.1039/P19930002017
(1993)
Sila-Reichstoffe und Riechstoffisostere XII. Geruchsvergleiche homologer Organoelementverbindungen der vierten Hauptgruppe (C, Si, Ge, Sn)

Doi:10.1016/0022-328X(93)80293-K
(1993)

Article Doi