M.X. Li et al. / Journal of Inorganic Biochemistry 106 (2012) 117–125
125
[11] S.C. Lim, K.A. Price, S.F. Chong, B.M. Paterson, A. Caragounis, K.J. Barnham, P.J.
Crouch, J.M. Peach, J.R. Dilworth, A.R. White, P.S. Donnelly, Journal of Biological
Inorganic Chemistry 15 (2010) 225–235.
effects than their parent ligand, which was consistent with their ac-
tions in MTT assay.
[12] T. Rosu, E. Pahontu, S. Pasculescu, R. Georgescu, N. Stanica, A. Curaj, A. Popescu, M.
Leabu, European Journal of Medicinal Chemistry 45 (2010) 1627–1634.
[13] C.R. Kowol, R. Trondl, V.B. Arion, M.A. Jakupec, I. Lichtscheidl, B.K. Keppler, Dalton
Transactions 39 (2010) 704–706.
[14] M.X. Li, C.L. Chen, C.S. Ling, J. Zhou, B.S. Ji, Y.J. Wu, J.Y. Niu, Bioorganic & Medicinal
Chemistry Letters 19 (2009) 2704–2706.
Abbreviations
HL1
2-benzoylpyridine S-methyldithiocarbazate
2-benzoylpyridine S-phenyldithiocarbazate
Mitochondria membrane potential
HL2
MMP
[15] M.X. Li, C.L. Chen, D. Zhang, J.Y. Niu, B.S. Ji, European Journal of Medicinal Chemistry
45 (2010) 3169–3177.
DMSO-d6 Deuterated dimethyl sulphoxide
[16] M.X. Li, D. Zhang, L.Z. Zhang, J.Y. Niu, Inorganic Chemistry Communications 13
(2010) 1268–1271.
[17] M.X. Li, D. Zhang, L.Z. Zhang, J.Y. Niu, B.S. Ji, Inorganic Chemistry Communications
13 (2010) 1572–1575.
[18] M.X. Li, D. Zhang, L.Z. Zhang, J.Y. Niu, B.S. Ji, Journal of Organometallic Chemistry
696 (2011) 852–858.
[19] G.M. Sheldrick, SHELXTL (Version 5.1), Bruker AXS Inc, Madison, Wisconsin (USA),
1997.
MIC
DMSO
MTT
Minimal inhibitory concentrations
Dimethyl sulphoxide
3-(4,5-Dimethylthiazol-2-yl)-2,5-diphenyltetrazolium
bromide
Phosphate-buffered saline
Propidine iodide
PBS
PI
MPT
Rh123
Mitochondrial permeability transition
Rhodamine 123
[20] S.A. Khan, K. Saleem, Z. Khan, European Journal of Medicinal Chemistry 42 (2007)
103–108.
[21] S. Singh, N. Bharti, F. Naqvi, A. Azam, European Journal of Medicinal Chemistry 39
(2004) 459–465.
[22] M.A. Ali, A.H. Mirza, M.H.S.A. Hamid, P.V. Bernhardt, O. Atchade, X. Song, G. Eng, L.
May, Polyhedron 27 (2008) 977–984.
[23] M.T.H. Tarafder, K. Chew, K.A. Crouse, A.M. Ali, B.M. Yamin, H.K. Fun, Polyhedron
21 (2002) 2683–2690.
Acknowledgements
[24] S. Shanmugam, S. Raj, B.M. Yamin, Y.A. Yusof, M.T.H. Tarafder, H.K. Fun, K.A.
Crouse, Acta Crystallographica C56 (2000) 1236–1237.
[25] M.A. Ali, A.H. Mirza, M.H.S.A. Hamid, P.V. Bernhardt, Polyhedron 24 (2005)
383–390.
[26] M. Baldini, M. Belicchi-Ferrari, F. Bisceglie, G. Pelosi, S. Pinelli, P. Tarasconi, Inor-
ganic Chemistry 42 (2003) 2049–2055.
This work was financially supported by the National Natural Sci-
ence Foundation of China (21071043), the China Postdoctoral Science
Foundation (20090460847) and the Natural Science Foundation of
the Educational Department of Henan Province (2010B150003).
[27] J. García-Tojal, M.K. Urtiaga, R. Cortés, L. Lezama, M.I. Arriortua, T. Rojo, Journal of
the Chemical Society Dalton Transactions (1994) 2233–2238.
[28] E.W. Ainscough, A.M. Brodie, J.D. Ranford, J.M. Waters, Journal of the Chemical
Society Dalton Transactions (1991) 1737–1742.
[29] A. Sreekanth, M.R.P. Kurup, Polyhedron 23 (2004) 969–978.
[30] S.M.M.H. Majumder, M.A. Ali, F.E. Smith, M.A.U. Mridha, Polyhedron 7 (1988)
2183–2187.
References
[1] A.B. Beshir, S.K. Guchhait, J.A. Gascón, G. Fenteany, Bioorganic & Medicinal Chem-
istry Letters 18 (2008) 498–504.
[2] T. Bal, B. Atasever, Z. Solakoğlu, S. Erdem-Kuruca, B. Ülküseven, European Journal
of Medicinal Chemistry 42 (2007) 161–167.
[3] P.K. Sasmal, A.K. Patra, A.R. Chakravarty, Journal of Inorganic Biochemistry 102
(2008) 1463–1472.
[31] M. Joseph, M. Kuriakose, M.R.P. Kurup, E. Suresh, A. Kishore, S.G. Bhat, Polyhedron
25 (2006) 61–70.
[4] M.E. Hossajn, M.N. Alam, M.A. Ali, M. Nazimuddin, F.E. Smith, R.C. Hynes, Polyhe-
dron 15 (1996) 973–980.
[5] M.E. Hossajn, M.N. Alam, J. Begum, M.A. Ali, M. Nazimuddin, R.C. Hynes, Inorga-
nica Chimica Acta 249 (1996) 207–213.
[6] J.P. Holland, F.I. Aigbirhio, H.M. Betts, P.D. Bonnitcha, P. Burke, M. Christlieb, G.C.
Churchill, A.R. Cowley, J.R. Dilworth, P.S. Donnelly, J.C. Green, J.M. Peach, S.R.
Vasudevan, J.E. Warren, Inorganic Chemistry 46 (2007) 465–485.
[7] H. Zhang, R. Thomas, D. Oupicky, F. Peng, Journal of Biological Inorganic Chemis-
try 13 (2008) 47–55.
[32] L. Thelander, A. Graslund, Journal of Biological Chemistry 258 (1983) 4063–4066.
[33] P.F. Iqbal, A.R. Bhat, A. Azam, European Journal of Medicinal Chemistry 44 (2009)
2252–2259.
[34] J.G. Tojal, A.G. Orad, J.L. Serra, J.L. Pizarro, L. Lezama, M.I. Arriortua, T. Rojo, Journal
of Inorganic Biochemistry 75 (1999) 45–54.
[35] S.K. Jain, B.S. Garg, Y.K. Bhoon, Spectrochim. Acta. A42 (1986) 959–968.
[36] H. Beraldo, D. Gambino, Mini Reviews in Medicinal Chemistry 4 (2004) 159–165.
[37] M.A.H. Mirza, R.J. Butcher, M.T.H. Tarafder, T.B. Keat, A.M. Ali, Journal of Inorganic
Biochemistry 92 (2002) 141–148.
[8] A.R. Cowley, J. Davis, J.R. Dilworth, P.S. Donnelly, R. Dobson, A. Nightingale, J.M.
Peach, B. Shore, D. Kerr, L. Seymour, Chemical Communications (2005) 845–847.
[9] R. Ruiz, B. García, J. Garcia-Tojal, N. Busto, S. Ibeas, J.M. Leal, C. Martins, J. Gaspar, J.
Borrás, R. Gil-García, M. González-Álvarez, Journal of Biological Inorganic Chemis-
try 15 (2010) 515–532.
[38] M. Das, S.E. Livingstone, British Journal of Cancer 37 (1978) 466–469.
[39] N. Farrell, Coordination Chemistry Reviews 232 (2002) 1–230.
[40] S. Singh, N. Bharti, P.P. Mohapatra, Chemical Reviews 109 (2009) 1900–1947.
[41] J.F. Turrens, Journal of Physiology 552 (2003) 335–344.
[42] I. Lizasoain, C.P. Weiner, R.G. Knowles, S. Moncada, Pediatric Research 39 (1996)
779–788.
[10] D. Dayal, D. Palanimuthu, S.V. Shinde, K. Somasundaram, A.G. Samuelson, Journal
of Biological Inorganic Chemistry 16 (2011) 621–632.