Tyrphostins. 3. Structure-Activity Relationship Studies of α-Substituted Benzylidenemalononitrile 5-S-Aryltyrphostins

DOI: 10.1021/jm00075a010

Source and publish data:

Journal of Medicinal Chemistry p. 3556 - 3564 (1993)

Update date:2022-08-03

Topics:

Authors:

Gazit, Aviv

Osherov, Nir

Posner, Israel

Bar-Sinai, Allan

Gilon, Chaim

Levitzki, Alexander

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Article abstract of DOI:10.1021/jm00075a010

In this study we describe an extension of our previous studies on cis-benzylidenemalononitrile tyrphostins.We have introduced S-aryl substituents in the 5 position (meta vis-a-vis the malononitrile moiety).We find that these compounds are potent blockers

Full text of DOI:10.1021/jm00075a010

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