Adenosine receptor prodrugs: Synthesis and biological activity of derivatives of potent, A1-selective agonists

Article abstract of DOI:10.1002/jps.2600830112

5'-Ester derivatives of the potent adenosine agonists N⁶-[4-[[[[4-[[[(2- acetylaminoethyl)amino]carbonyl]methyl]anilino]carbonyl]methyl]phenyl]adenosi ne (N-AcADAC; 1) and N⁶-cyclopentyladenosine (CPA; 2) were prepared as prodrugs. B