Synthesis of Acyclic Polyol Derivatives via Enzyme-Mediated Aldol Reaction

DOI: 10.1016/S0040-4039(00)74050-0

Source and publish data:

Tetrahedron Letters p. 4935 - 4938 (1993)

Update date:2022-07-29

Topics:

Authors:

Matsumoto, Kazutsugu

Shimagaki, Masayuki

Nakata, Tadashi

Oishi, Takeshi

Read Full Text PDF DownLoad Join now for total 90,000,000 free articles

Article abstract of DOI:10.1016/S0040-4039(00)74050-0

Enzyme-mediated stereoselective aldol reaction between dihydroxyacetone phosphate (DHAP, 1) and (2R,4R)-6-benzyloxy-2,4-dimethoxyhexanal (8) was catalyzed by rabbit muscle aldolase (RAMA) to generate (3S,4R,5R,7R)-trihydroxyketone 12, which could be easily transformed to the masked polyhydroxylated compound 15 corresponding to the C-9-C-16 segment of pentamycin (6).

Full text of DOI:10.1016/S0040-4039(00)74050-0

Products guided by the article

Product name:(2R,4R)-6-benzyloxy-2,4-dimethoxyhexanal

Cas No:152035-83-1

R&D Labs maybe for 152035-83-1

Shandong Xinke Petrochemical Co., Ltd.

Contact:+86-546-7277016

Address:Gudao Industrial Park, Hekou District, Dongying, Shandong Province, China
YanCheng LongShen Chemical Co.,Ltd.

Contact:+86-515-86668866

Address:No.13,Weiyi Road,Funing Aoyang Industrial Park
Wuhan Pengo Technology.,Ltd.

Contact:+86-27-67841589

Address:Add: 999 Gaoxin Road, Donghu New Technology Development Zone, Wuhan City, Hubei, China
QINGDAO ON-BILLION INDUSTRAIL CO.,LTD

website:http://www.obn.com.cn

Contact:+86-15005320811 +86-532-80681989

Address:F35 Parkson Mansion No.44-60 Zhongshan Rd.
Beijing Mediking Biopharm Co., Ltd.

Contact:+86-10-89753524/81760121/81769521

Address:Hongxianghong Incubator, Beiqijia Town, Changping district, Beijing, China

Relevant to this article

N-<(1-Butyl-4-piperidinyl)methyl>-3,4-dihydro-2H-<1,3>oxazino<3,2-α>indole-10-carboxamide Hydrochloride: The First Potent and Selective 5-HT₄ Receptor Antagonist Amide with Oral Activity

Doi:10.1021/jm00024a002
(1995)
Stereoselective synthesis of stable isotope-labeled L-α-amino acids: Electrophilic amination of oppolzer's acyl sultams in the synthesis of L-[¹⁵N]alanine, L-[¹⁵N]valine, L-[¹⁵N]leucine, L-[¹⁵N]phenylalanine and

Doi:10.1002/(SICI)1099-1344(199603)38:3<239::AID-JLCR831>3.0.CO;2-E
(1996)
Doi:10.1021/jo01268a066
(1968)
Thermal decomposition of N-alkylated-2-amino-benzophenones

Doi:10.3987/COM-08-11626
(2009)
Doi:10.1039/j39670001178
(1967)
Cholic Acid Derived Novel Chiral Auxiliaries for Asymmetric Diels-Alder Reactions

Doi:10.1039/c39930001469
(1993)

Article Doi