Tetrahedron Letters p. 4149 - 4152 (1993)
Update date:2022-08-04
Topics:
Ojima, Iwao
Sun, Chung Ming
Zucco, Martine
Park, Young Boon
Duclos, Olivier
Kuduk, Scott
Taxotere, a highly promising anticancer drug, is synthesized through an efficient coupling of 7,10-diTroc-10-deacetylbaccatin III with enantiomerically pure (3R,4S)-1-tBOC-3-EEO- 4-phenylazetidin-2-one which is obtained via chiral ester enolate - imine cyclocondensation.
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Doi:10.1021/ol403393w
(2014)Doi:10.1039/c3cc47045h
(2014)Doi:10.1016/j.tetlet.2013.10.106
(2014)Doi:10.1016/S0277-5387(00)88260-1
(1993)Doi:10.1021/jo01266a034
(1968)Doi:10.1021/jo00077a044
(1993)
