Asymmetric 1,2-Addition of Organolithiums to Aldimines Catalyzed by Chiral Ligand

Article abstract of DOI:10.1016/S0040-4020(01)89376-5

An asymmetric 1,2-addition reaction of organolithiums with imines 3, 7 was catalyzed by a 0.05-1.3 equivalent of a chiral amino ether 2 to provide the corresponding optically active amines 4, 8.