Diels-Alder reaction of 2′,3′-unsaturated-3′-nitro-thymidine. First chemical evidence of nitroxide radical formation in the radical-promoted denitration reaction

Article abstract of DOI:10.1016/S0040-4020(01)91224-4

Diels-Alder reaction of an appropriately functionalized nucleoside [2′,3′-dideoxy-2′,3′-didehydro-3′-nitrothymidine (1)] has been used for the first time as a substrate to yield various unique fused 2′,3′-dideoxy-2′,3′-bis-substituted nucleoside derivativ