Phe3-substituted analogues of deltorphin C. Spatial conformation and topography of the aromatic ring in peptide recognition by δ opioid receptors

Article abstract of DOI:10.1021/jm00076a001

In order to study the contribution of the electronic, hydrophobic, and conformational properties of the amino acid residue at position 3 in deltorphin C on binding to δ and μ opioid receptors, a series of 5- and 6- membered ring and bicyclic amino acid re