Preparation of chiral cyclobutane derivatives: Enantioselective syntheses of the key intermediates for cyclobutane monoterpenes, grandisol and lineatin

Article abstract of DOI:10.1016/S0957-4166(00)80356-0

Enantioselective synthesis of the key intermediates for cyclobutane monoterpenes, grandisol and lineatin was achieved by employing an enantioselective reduction of the prochiral cyclobutenone derivative as a key step.