Inhibitors of endo-α-mannosidase. Part I. Derivatives of 3-O-(α-D-glucopyranosyl)-D-mannopyranose

DOI: 10.1139/v93-239

Source and publish data:

Canadian Journal of Chemistry p. 1919 - 1927 (1993)

Update date:2022-09-26

Topics:

Authors:

Spohr Spohr

Bach Bach

Spiro Spiro

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Article abstract of DOI:10.1139/v93-239

Golgi membrane endo-α-D-mannosidase releases the disaccharide αDGlc(1 → 3)DMan (34) from the GlcMan₉GlcNAc₂ oligosaccharide of immature N-linked glycoproteins. To convert the hydrolysis product 34 into a potent inhibitor of the enzym

Full text of DOI:10.1139/v93-239

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