Synthesis and biological evaluation of a new series of sterols as potential hypocholesterolemic agents

DOI: 10.1021/jm00002a010

Source and publish data:

Journal of Medicinal Chemistry p. 277 - 288 (1995)

Update date:2022-08-04

Topics:

Authors:

Lin Lin

Rampersaud

Archer Archer

Pawlak Pawlak

Beavers Beavers

Schmidt Schmidt

Kauffman

Bensch Bensch

Bumol Bumol

Apelgren

Eacho Eacho

Perry Perry

McClure McClure

Gadski Gadski

Read Full Text PDF DownLoad Join now for total 90,000,000 free articles

Article abstract of DOI:10.1021/jm00002a010

A new series of sterols was synthesized and tested in a CHO cell-based LDL receptor/luciferase (LDLR/Luc) assay to investigate the capability of derepressing the transcription of LDL receptor promoter in the presence of 25-hydroxycholesterol. The effect o

Full text of DOI:10.1021/jm00002a010

Products guided by the article

Product name:(4S,5S,8S,9S,10R,13R,14S,17R)-17-((R)-1,5-Dimethyl-hexyl)-4-(4-fluoro-benzyl)-10,13-dimethyl-hexadecahydro-cyclopenta[a]phenanthren-3-one

Cas No:152755-39-0

R&D Labs maybe for 152755-39-0

Tianjin Tensing Fine Chemical Research Develop Centre

Contact:86-022-23718576,13032267585

Address:2-2-201,13 Guiyuan road,Huayuan Industry district,Tianjin,china
Luzhou North Chemical Co., Ltd.

Contact:+86-830-2796784；+86-830-2796776

Address:Gaoba, Longmatan District, Luzhou, Sichuan Province
GenicBio Limited

Contact:+86-(0)21-3770 9035

Address:Room 301, Building 2, Meijiabang Road 1508, Shanghai China
Nanjing Norris Pharm Technology Co., Ltd.

Contact:+86-13901585132

Address:2 Qiande Road, Jiangning sciencepark Hi-Tech Zone, Nanjing, P.R.China
jintan yufan Medicine Raw materials Co.,Ltd.(expird)

Contact:86-519-82808282

Address:6th,Jincheng Huangzhuang

Relevant to this article

Fragment based discovery of arginine isosteres through REPLACE: Towards non-ATP competitive CDK inhibitors

Doi:10.1016/j.bmc.2013.10.039
(2014)
Rapid defunctionalization of carbonyl group to methylene with polymethylhydrosiloxane-B(C₆F₅)₃

Doi:10.1021/jo0204045
(2002)
Synthesis, structure, and biological activity of the cis-[4-amino-2,2,6,6- tetramethylpiperidine-N,N′]dichloropalladium(ii) complex

Doi:10.1007/s11172-013-0080-7
(2013)
One-pot synthesis of d-glucosamine and chitobiosyl building blocks catalyzed by triflic acid on molecular sieves

Doi:10.1039/c3cc48078j
(2014)
Asymmetric dihydroxylation of linalool, nerolidol and citronellyl acetate. Enantioselective synthesis of (3S, 6S)-tetrahydro-2,2,6-trimethyl-6-vinyl-2H-pyran-3-ol

Doi:10.1016/S0040-4039(00)91832-X
(1993)
Bis(cyclopentadienyliron)arene Complexes: A new route to the synthesis and functionalization of polyaromatic ethers

Doi:10.1021/om00013a055
(1994)

Article Doi