Synthesis and biological evaluation of a new series of sterols as potential hypocholesterolemic agents

DOI: 10.1021/jm00002a010

Source and publish data:

Journal of Medicinal Chemistry p. 277 - 288 (1995)

Update date:2022-08-04

Topics:

Authors:

Lin Lin

Rampersaud

Archer Archer

Pawlak Pawlak

Beavers Beavers

Schmidt Schmidt

Kauffman

Bensch Bensch

Bumol Bumol

Apelgren

Eacho Eacho

Perry Perry

McClure McClure

Gadski Gadski

Read Full Text PDF DownLoad Join now for total 90,000,000 free articles

Article abstract of DOI:10.1021/jm00002a010

A new series of sterols was synthesized and tested in a CHO cell-based LDL receptor/luciferase (LDLR/Luc) assay to investigate the capability of derepressing the transcription of LDL receptor promoter in the presence of 25-hydroxycholesterol. The effect o

Full text of DOI:10.1021/jm00002a010

Products guided by the article

Product name:(4S,5S,8S,9S,10R,13R,14S,17R)-17-((R)-1,5-Dimethyl-hexyl)-4-(4-fluoro-benzyl)-10,13-dimethyl-hexadecahydro-cyclopenta[a]phenanthren-3-one

Cas No:152755-39-0

R&D Labs maybe for 152755-39-0

Nanjing HuiBaiShi Biotechnology Co.,Ltd.

Contact:+86 (25)58745219

Address:No.606 Ningliu Road,LiuHe District.
Changzhou Kingyo Chemical Corporation Ltd.

website:http://www.kingyochem.com

Contact:+86-519-85105717

Address:19# Wuqing North Road, Changzhou , Jiangsu, China
RongCheng Tianyu Technology Co.,Ltd.

Contact:86-631-7519595

Address:220Ping Donghai Road RongChengCity,ShangDong Province China
Lanzhou SchiffChem Co.,Ltd

Contact:86-931-8272767

Address:Room 602, No.461, Nanchang Road, Chengguan District, Lanzhou City, China PRC
Nanjing lanbai chemical Co.,Ltd.

Contact:+86-25-85499326

Address:Room 908, 9F Taiyue Building,No.285 Heyan Road

Relevant to this article

Fragment based discovery of arginine isosteres through REPLACE: Towards non-ATP competitive CDK inhibitors

Doi:10.1016/j.bmc.2013.10.039
(2014)
Rapid defunctionalization of carbonyl group to methylene with polymethylhydrosiloxane-B(C₆F₅)₃

Doi:10.1021/jo0204045
(2002)
Synthesis, structure, and biological activity of the cis-[4-amino-2,2,6,6- tetramethylpiperidine-N,N′]dichloropalladium(ii) complex

Doi:10.1007/s11172-013-0080-7
(2013)
One-pot synthesis of d-glucosamine and chitobiosyl building blocks catalyzed by triflic acid on molecular sieves

Doi:10.1039/c3cc48078j
(2014)
Asymmetric dihydroxylation of linalool, nerolidol and citronellyl acetate. Enantioselective synthesis of (3S, 6S)-tetrahydro-2,2,6-trimethyl-6-vinyl-2H-pyran-3-ol

Doi:10.1016/S0040-4039(00)91832-X
(1993)
Bis(cyclopentadienyliron)arene Complexes: A new route to the synthesis and functionalization of polyaromatic ethers

Doi:10.1021/om00013a055
(1994)

Article Doi