Synthesis and biological evaluation of a new series of sterols as potential hypocholesterolemic agents

DOI: 10.1021/jm00002a010

Source and publish data:

Journal of Medicinal Chemistry p. 277 - 288 (1995)

Update date:2022-08-04

Topics:

Authors:

Lin Lin

Rampersaud

Archer Archer

Pawlak Pawlak

Beavers Beavers

Schmidt Schmidt

Kauffman

Bensch Bensch

Bumol Bumol

Apelgren

Eacho Eacho

Perry Perry

McClure McClure

Gadski Gadski

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Article abstract of DOI:10.1021/jm00002a010

A new series of sterols was synthesized and tested in a CHO cell-based LDL receptor/luciferase (LDLR/Luc) assay to investigate the capability of derepressing the transcription of LDL receptor promoter in the presence of 25-hydroxycholesterol. The effect o

Full text of DOI:10.1021/jm00002a010

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