Synthesis and biological activity of 4′-thio-2′-deoxy purine nucleosides

Article abstract of DOI:10.1080/15257779908041540

Coupling of 1-O-acetyl-2-deoxy-3,5-di-O-toluoyl-4-thio-D-ribofuranose with 6-chloropurine and 2,6-dichloropurine gave a mixture of 9α and 9β anomers as major products. These anomers were separated and converted to 2′-deoxy-4′-thio analogues of adenosine, inosine, guanosine, 2-amino-adenosine, and 2-chloro adenosine as well as their α-anomers. Copyright

Full text of DOI:10.1080/15257779908041540

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Nucleosides and Nucleotides
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Synthesis and Biological Activity of 4′-
Thio-2′-deoxy Purine Nucleosides
Lea Messini a , Kamal N. Tiwari a , John A. Montgomery a & John A.
Secrist III a
a Southern Research Institute , P.O. Box 55305, Birmingham, AL,
35255-5305, USA
Published online: 04 Oct 2006.
To cite this article: Lea Messini , Kamal N. Tiwari , John A. Montgomery & John A. Secrist III (1999)
Synthesis and Biological Activity of 4′-Thio-2′-deoxy Purine Nucleosides, Nucleosides and Nucleotides,
18:4-5, 683-685, DOI: 10.1080/15257779908041540
To link to this article: http://dx.doi.org/10.1080/15257779908041540
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