New N-ethanethiol pyrroles as radioprotectors

DOI: 10.1016/0223-5234(93)90029-E

Source and publish data:

European Journal of Medicinal Chemistry p. 703 - 707 (1993)

Update date:2022-08-05

Topics:

Authors:

Law-Ho Law-Ho

Pera Pera

Taillandier

Fatome Fatome

Laval Laval

Leclerc Leclerc

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Article abstract of DOI:10.1016/0223-5234(93)90029-E

Seventeen N-ethanethiol pyrroles have been prepared and tested as radioprotective agents. This is the first time that pyrrole compounds with radioprotective activity have been reported. The dimethyl pyrrole derivative 3a and its corresponding disulfur 4a exhibited strong long-lasting effects.

Full text of DOI:10.1016/0223-5234(93)90029-E

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