Journal of Medicinal Chemistry p. 226 - 231 (1994)
Update date:2022-07-30
Topics:
Oleksyszyn, Jozef
Boduszek, Bogdan
Kam, Chih-Min
Powers, James C.
A series of new peptidyl(α-aminoalkyl)phosphonate diphenyl esters containing the 4-amidinophenyl group were synthesized and tested as irreversible inhibitors for thrombin and other trypsin-like enzymes.These phosphonates irreversibly inhibited several coa
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