Preparation and antitumor activity of an N-methylcarbamate derivative of amsacrine

DOI: 10.1016/0223-5234(93)90045-G

Source and publish data:

European Journal of Medicinal Chemistry p. 913 - 916 (1993)

Update date:2022-09-26

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Authors:

El-Hamouly

Ruckdeschel

Archer Archer

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Article abstract of DOI:10.1016/0223-5234(93)90045-G

An amsacrine derivative 10 containing an N-methylcarbamate residue was synthesized and tested for cytotoxicity in 4 human lung cancer cell lines along with amsacrine and adriamycin. The N-methyl-carbamate appeared to be as active as adriamycin and somewha

Full text of DOI:10.1016/0223-5234(93)90045-G

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