Improved routes to homologated isoxazoles

DOI: 10.1080/00397919408011199

Source and publish data:

Synthetic Communications p. 399 - 407 (1994)

Update date:2022-08-04

Topics:

Authors:

Meikrantz

Smith Smith

Xia Xia

Natale Natale

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Article abstract of DOI:10.1080/00397919408011199

Two carbon homologation of isoxazole-4-carbinols was performed by reaction of lithio-2,4,4-trimethyl-Δ²-oxazoline 1 with 4-chloromethyl-isoxazole 2, followed by trans-esterification and reduction to the isoxazole-4-propanols 5a and b. Alternati

Full text of DOI:10.1080/00397919408011199

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