Synthetic Communications p. 1683 - 1689 (2001)
Update date:2022-08-03
Topics:
Klepacz
Zwierzak
The reactions between diethyl N-(t-butoxycarbonyl)phosphoramidate 1, diisopropyl azodicarboxylate (DIAD), triphenylphosphine (TPP) and primary or secondary alcohols lead to the corresponding diethyl N-alkyl-N-(t-butoxycarbonyl)phosphoramidates 2a-o. Deprotection of crude 2 by refluxing with p-toluenesulfonic acid monohydrate in ethanol affords ammonium tosylates 3a-o in moderate to good overall yields. The N-alkylation of 1 proceeds stereoselectively with complete inversion of the configuration of the alkyl group.
View MoreShandong LuZhou Amino Acid Co., Ltd
Contact:86-539-2218025
Address:yishui economic and technical development zone zhenxing south road
website:http://www.alwaychem.com
Contact:+86-532-8586-4000, 8586-5000
Address:NO.51, TAIPING ROAD, QINGDAO, CHINA. 266001
Wuhan Chemwish Technology Co., Ltd
website:http://www.chemwish.com/
Contact:+86-27-67849912
Address:Room 1311, Unit 2, Block1, Innovation Road East Lake High-tech Development Zone Wuhan, Hubei,P.R. China
Zhangjiagang Jianing Import & Export Co.,Ltd.
Contact:086-512-55379012 13913607595
Address:NO.1 Guotai North Road Zhangjiagang Economic Development Zone,215600,Jiangsu,China
Henan Techway Chemical Co.,Ltd.
website:http://www.techwaychem.com
Contact:+86-371-66380080
Address:No.27 Shunhe Road,
Doi:10.1002/hlca.19930760803
(1993)Doi:10.1002/jhet.5570300446
(1993)Doi:10.1002/jhet.5570300610
(1993)Doi:10.1246/cl.1976.611
(1976)Doi:10.1021/jo00080a014
(1994)Doi:10.1016/j.bmc.2013.11.020
(2014)