Studies of HIV-1 protease inhibitors. I. Incorporation of a reduced peptide, simple aminoalcohol, and statine analog at the scissile site of substrate sequences

DOI: 10.1248/cpb.41.1369

Source and publish data:

Chemical and Pharmaceutical Bulletin p. 1369 - 1377 (1993)

Update date:2022-08-03

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Authors:

Sakurai Sakurai

Sugano Sugano

Handa Handa

Komai Komai

Yagi Yagi

Nishigaki

Yabe Yabe

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Article abstract of DOI:10.1248/cpb.41.1369

Inhibitors of the protease of human immunodeficiency virus type-1 (HIV-1) were designed and synthesized. A reduced peptide, simple aminoalcohol, and statine analog, 4-amino-3-hydroxy-5-phenylpentanoic acid (AHPPA), were inserted at the scissile site of su

Full text of DOI:10.1248/cpb.41.1369

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